Effects of radiotherapy in patients with nasopharyngeal carcinoma under continuous-discrete mixed mathematical model and comparison on the fungal and pathogen infection indexes before and after nutritional supplementation

dc.contributor.author Li, Yi
dc.contributor.author Li, Xuan
dc.contributor.author Issa, Sahar
dc.contributor.author Omar, Khairi Mohamed
dc.date.accessioned 2021-06-16T13:53:19Z
dc.date.available 2021-06-16T13:53:19Z
dc.date.copyright 2021
dc.date.issued 2021-07
dc.description This article is not available at CUD collection. The version of scholarly record of this article is published in Results in Physics (2021), available online at: https://doi.org/10.1016/j.rinp.2021.104355 en_US
dc.description.abstract The study aimed to explore the effects of radiotherapy on nasopharyngeal carcinoma (NPC) patients before and after nutritional supplementation, and the correlation between nutritional supplementation and infections, using continuous-discrete mixed mathematical model. Specifically, 398 NPC patients were selected based on information and health data. They all accepted radiation therapy, and enteral nutrition was provided through nasal feeding during the radiotherapy. Then, nutritional indicators, and infections were compared before and after nutritional supplementation. The results showed that, the radio-sensitivity coefficient and the age of tumor cells affected radiotherapy effects. After nutritional supplementation, the patient's Hemoglobin (Hb) was 139.26 ± 12.87 g/L, the serum albumin (ALB) was 45.65 ± 3.84 g/ L, the Lymphocyte (LYM) was 1.96 ± 0.68 (×109/L), and the Body Mass Index (BMI) was 26.12 ± 2.63 (kg/m2). Among them, Hb, LYM, and BMI were notably different from those before treatment (P < 0.05). After nutritional supplementation, the infection rates of Candida albicans, Candida tropicalis, Saccharomyces cerevisiae, Candida, and actinomycetes were reduced to 26.09%, 17.39%, 9.78%, 5.43%, and 1.09%, respectively, showing notable differences (P < 0.05); the infection rates of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, pyogenic chain Coccus, Staphylococcus epidermidis, and Streptococcus viridans were reduced to 15.27%, 12.21%, 3.82%, 6.11%, 0.76%, and 0.76%, respectively, showing notable differences (P < 0.05). In conclusion, the continuous-discrete mixed mathematical model can simulate the effects of radiotherapy on NPC patients. Nutritional supplementation during radiotherapy can reduce the infection rates, thus improving the prognosis of NPC patients. © 2021 The Author(s) en_US
dc.identifier.citation Li, Y., Li, X., Issa, S., & Omar, K. M. (2021). Effects of Radiotherapy in Patients with Nasopharyngeal Carcinoma under Continuous-discrete Mixed Mathematical Model and Comparison on the Fungal and Pathogen Infection Indexes Before and After Nutritional Supplementation. Results in Physics, 26, 104355. https://doi.org/10.1016/j.rinp.2021.104355 en_US
dc.identifier.issn 22113797
dc.identifier.uri https://doi.org/10.1016/j.rinp.2021.104355
dc.identifier.uri http://hdl.handle.net/20.500.12519/390
dc.language.iso en en_US
dc.publisher Elsevier B.V. en_US
dc.relation Authors Affiliations : Li, Y., Department of Otolaryngology, the 988th Hospital of the Joint Support Force of the Chinese People's Liberation Army, Zhengzhou City 450042, Henan Province, China; Li, X., Laboratory of Blood Transfusion, 988th Hospital of Chinese PLA, Zhengzhou City 450042, Henan Province, China; Issa, S., Department of Environmental Health Sciences, Faculty of Communication, Arts and Sciences, Canadian University Dubai, Dubai, United Arab Emirates; Omar, K.M., Applied Science University, Al Eker, Bahrain
dc.relation.ispartofseries Results in Physics;Volume 26
dc.rights Creative Commons CC-BY-NC-ND License
dc.rights.holder Copyright : © 2021 The Author(s)
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject Computer information health data en_US
dc.subject Continuous-discrete mixed mathematical model en_US
dc.subject Fungal and pathogen infection en_US
dc.subject Nasopharyngeal carcinama en_US
dc.title Effects of radiotherapy in patients with nasopharyngeal carcinoma under continuous-discrete mixed mathematical model and comparison on the fungal and pathogen infection indexes before and after nutritional supplementation en_US
dc.type Article en_US
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